BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//talks.cam.ac.uk//v3//EN
BEGIN:VTIMEZONE
TZID:Europe/London
BEGIN:DAYLIGHT
TZOFFSETFROM:+0000
TZOFFSETTO:+0100
TZNAME:BST
DTSTART:19700329T010000
RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=-1SU
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0100
TZOFFSETTO:+0000
TZNAME:GMT
DTSTART:19701025T020000
RRULE:FREQ=YEARLY;BYMONTH=10;BYDAY=-1SU
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
CATEGORIES:Parasitology Seminars
SUMMARY:Finding a needle in a haystack: Genome-wide analys
 es of anthelmintic resistance in helminths of live
 stock - Dr Roz Laing (University of Glasgow)
DTSTART;TZID=Europe/London:20220615T160000
DTEND;TZID=Europe/London:20220615T170000
UID:TALK173873AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/173873
DESCRIPTION:Control of parasitic infections in animals and hum
 ans currently relies on mass drug administration o
 f a limited number of anthelmintics. However\, thi
 s is not sustainable due to the emergence and spre
 ad of anthelmintic resistance. Haemonchus contortu
 s is a highly pathogenic gastrointestinal nematode
  of small ruminants\, which is becoming increasing
 ly difficult to control due to multi-drug resistan
 ce. The mechanisms underlying anthelmintic resista
 nce are generally poorly understood\, with studies
  comparing resistant and sensitive parasites confo
 unded by high levels of genetic diversity within a
 nd between and populations. To overcome this\, we 
 crossed a well-characterised multi-drug resistant 
 isolate of H. contortus with a drug susceptible is
 olate to study resistance to three major anthelmin
 tic classes\, while controlling for background var
 iation. In this talk I will focus on our genomic a
 nd transcriptomic analyses of ivermectin resistanc
 e and describe ongoing work investigating the evol
 ution of multi-drug resistance in H. contortus and
  related parasites.\n\nThis talk will be broadcast
 ed via Zoom. Please use this "link":https://zoom.u
 s/j/95026514738?pwd=aUtoam1zbDRYYWU0M1Nob2VPQXNvZz
 09 to gain access. 
LOCATION:Department of Pathology Lecture Theatre
CONTACT:Anna Protasio
END:VEVENT
END:VCALENDAR