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CATEGORIES:Computational Neuroscience
SUMMARY:Computational Neuroscience Journal Club - Yashar A
 hmadian
DTSTART;TZID=Europe/London:20200630T163000
DTEND;TZID=Europe/London:20200630T180000
UID:TALK149803AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/149803
DESCRIPTION:Please join us for our fortnightly journal club on
 line via zoom where two presenters will jointly pr
 esent a topic together.\n\nZoom info:\nhttps://us0
 2web.zoom.us/j/82267089859?pwd=WXpTMzNadHZDQnZkQWt
 rcFVqMk9KUT09\nMeeting ID: 822 6708 9859\nPassword
 : 223170\n\nThe next topic is 'sensory-motor integ
 ration in V1' presented by Yashar Ahmadian and Ell
 iott Abe. Here is a brief summary of the journal c
 lub:\n\nIn the textbook view\, the activity in the
  primary visual cortex is assumed to primarily rep
 resent the current visual stimulus. This simplific
 ation has been especially challenged by various st
 udies of the past decade in mouse V1\, indicating 
 that various contextual and motor-behavioral varia
 bles strongly affect V1 activity and explain much 
 of its variance. \nA famous example is the amplifi
 cation of V1 responses during locomotion. Several 
 findings indicate that the effect of locomotion on
  V1 is more complex than just a global change of g
 ain\, and should be viewed in the broader context 
 of sensory-motor integration. An animal's self-mot
 ion has sensory consequences that tend to be highl
 y predictable (e.g. self-motion causes optic flow)
 . The brain can in principle build an internal mod
 el of these "reafference signals"\, and use "effer
 ence copies" of its own motor commands in order to
  filter out those predictable consequences so that
  neural responses (in at least a subset of neurons
 ) can represent the less predictable and more rele
 vant aspects of external sensory inputs -- or so g
 oes (one interpretation of) one specific flavor of
  the predictive coding hypothesis. In this JC we w
 ill review some of the evidence for such predictiv
 e coding in mouse V1 and the circuit mechanisms im
 plementing it.  \n \nWe (my student Elliott Abe an
 d I) will focus on these papers: \n- https://www.b
 iorxiv.org/content/10.1101/2020.03.25.008607v1\n- 
 https://linkinghub.elsevier.com/retrieve/pii/S0092
 -8674(17)30583-4\n- (time allowing) https://www.sc
 iencedirect.com/science/article/pii/S0896627317307
 791\n\n\n
LOCATION:Online on Zoom
CONTACT:Jake Stroud
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