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SUMMARY:Minimal and Ancestral Genomes - Dr. Arcady Mushegian from National
  Science Foundation\, USA 
DTSTART:20191121T140000Z
DTEND:20191121T150000Z
UID:TALK133540@talks.cam.ac.uk
CONTACT:Caroline Newnham
DESCRIPTION:Minimal genome is a construct of biochemical engineering\; it 
 is a cell that may survive under given growth conditions with the smallest
  amount of genetic material\, and the research question here is how to det
 ermine what that material should be. Ancestral genome is a construct of ev
 olutionary inference\; it is a cell that may represent the last common anc
 estor of a given set of evolutionary lineages\, and the question here is h
 ow to retrodict what the ancestral genome was. Different as the two questi
 ons are\, the answers to both of them are provided with the aid of computa
 tional biology\, when the genomes of many species known today are compared
  to each other. I will discuss what has been learned about minimal and anc
 estral genomes thus far in the course of my own computational biology rese
 arch as well as the computational and experimental work done by many other
 s. 
LOCATION:Part II Room\, Department of Genetics\, Downing Site
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