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SUMMARY:Equine Rotavirus Diarrhoea in Neonates: Situation in Argentina and
  optimisation of prevention and therapeutic methods - Dr Aldana Vissani\, 
 Institudo de Investigación Virología\, Instituto Nacional de Tecnologia 
 Agropecuaria\, Buenos Aires\, Argentina
DTSTART:20191009T150000Z
DTEND:20191009T160000Z
UID:TALK128125@talks.cam.ac.uk
CONTACT:Theodora Anderson
DESCRIPTION:Diarrhoea in foals is one of the most important clinical condi
 tions for sport horse breeding establishments. The principal causal agent 
 of diarrhoea in foals is Equine Rotavirus group A\, with two different var
 iants\, G3P [12] and G14P [12]\, distributed throughout the world. In inte
 nsive breeding establishments in Argentina\, the morbidity of rotavirus di
 arrhoea in foals is around 30%. Argentina is the fourth largest producer o
 f Thoroughbred horses in the world\, and the largest producer of Polo hors
 es\, thus losses caused by outbreaks of Rotavirus diarrhoea in foals are e
 conomically significant. Prevention of rotavirus diarrhoea is based on vac
 cination of pregnant mares\, with a vaccine containing Equine Rotavirus gr
 oup A. This was previously developed by our group and transferred to the i
 ndustry in 1996. This vaccine only contains the strain G3P [12]\, which wa
 s the most predominant strain circulating. However\, during recent years\,
  an increased prevalence of the G14P [12] strain has been observed. Our gr
 oup is currently working to reduce incidence of rotavirus in foals by two 
 methods\; firstly by generating a vaccine containing both circulating stra
 ins of Equine Rotavirus\, and secondly by developing a passive immune stra
 tegy based on IgY antibodies\, to be used in those foals in which a failur
 e in transfer of immunity from the mare has occurred.
LOCATION:Lecture Theatre 2\, Department of Veterinary Medicine
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