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SUMMARY:Serotonergic modulation of emotion and cognition: the search for s
 pecific functions and future research directions - Clark Roberts\, The LeD
 oux Lab\, Center for Neural Science\, NY Univ
DTSTART:20190225T123000Z
DTEND:20190225T133000Z
UID:TALK120943@talks.cam.ac.uk
CONTACT:Lorraine Coulson
DESCRIPTION:The serendipitous emergence of MAOI's\, Tricyclics\, and SSRIs
  catalyzed increased research interest in serotonin. Early methodologies r
 elied on subjective questionnaires to assess primarily treatment efficacy 
 outcomes. Thus little is known still about the impact of serotonin modulat
 ion on more objective measures of learning\, cognition\, and emotion. Prob
 lems remain with context-specificity in treatment outcomes\, acute vs chro
 nic effects\, drug target specificity\, and inter-subject variability. Whi
 le popular culture stereotypes serotonin as the mood neurotransmitter\, ne
 uroscience research has yet to find any single coherent functional underst
 anding of 5-HT. Rather\, it has found many 5-HT mechanisms and functions\,
  but with a less unified understanding compared to other neuromodulators. 
 I will discuss why psychiatry and neuroscience has yet to find an all-enco
 mpassing function of serotonin\, some of the difficulties in parsing 5-HT 
 functionality in the literature\, some recent research on the role of sero
 tonin in cognitive flexibility\, and how future research might more direct
 ly target the mechanisms and functions of serotonin in cognition and emoti
 on.
LOCATION:Kenneth Craik Room\, Craik Marshall Building\, Downing Site\, Cam
 bridge
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