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CATEGORIES:MRC Mitochondrial Biology Unit Seminars
SUMMARY:Mitochondrial DNA maintenance in non-standard mode
 l systems - Professor Torsten Ochsenreiter | Unive
 rsity of Bern 
DTSTART;TZID=Europe/London:20191016T150000
DTEND;TZID=Europe/London:20191016T160000
UID:TALK120406AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/120406
DESCRIPTION:Trypanosomes are single celled eukaryotes that are
  only distantly related to the major model systems
  for mitochondrial biology\, like yeast\, mouse or
  human. Different from these model systems trypano
 some cells contain only one mitochondrial organell
 e with a singular genome (mt-genome). Replication 
 and segregation of the mt-genome is tightly integr
 ated into the cell cycle and a large number of pro
 teins are involved in these two processes. In rece
 nt years we and others used a combination of bioch
 emical and super resolution microscopy approaches 
 to characterized the molecular components involved
  in proper segregation. We have now a model that d
 escribes the assembly of the segregation machinery
  that spans the cytoplasm\, the two mitochondrial 
 membranes as well as the mitochondrial matrix. The
  presentation will also aim to compare the current
  status in trypanosomes to the other major model s
 ystems.
LOCATION:Sackler Lecture Theatre (Level 7) The Keith Peters
  Building\, Cambridge Biomedical Campus
CONTACT:Hannah Burns
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