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CATEGORIES:Biophysical Seminars
SUMMARY:Cellular responses to DNA damage: mechanistic insi
 ghts and therapeutic applications - Prof. Steve Ja
 ckson\, University of Cambridge
DTSTART;TZID=Europe/London:20181031T103000
DTEND;TZID=Europe/London:20181031T113000
UID:TALK114004AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/114004
DESCRIPTION:Very recent scientific and technological breakthro
 ughs now allow researchers to study fundamental as
 pects of human cell biology with hitherto unimagin
 able depth\, breadth and precision. Using paradigm
 s derived from my academic laboratory – one of whi
 ch has led to the drug olaparib/LynparzaTM that is
  being used to treat cancer patients worldwide –  
 I will highlight how “blue skies” research into ce
 ll function can provide insights into disease mech
 anisms and identify new opportunities for alleviat
 ing cancer. I will also explain how the approaches
  that my laboratory uses may have utility in the c
 ontext of human diseases associated with protein m
 isfolding and/or aggregation. 
LOCATION:Department of Chemistry\, Cambridge\, Unilever lec
 ture theatre
CONTACT:Will Arter
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