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CATEGORIES:Computational and Systems Biology
SUMMARY:Discovering the gene networks that regulate hunger
  - Dr Katherine Lawler (MRC Institute of Metabolic
  Science)
DTSTART;TZID=Europe/London:20181107T140000
DTEND;TZID=Europe/London:20181107T150000
UID:TALK111562AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/111562
DESCRIPTION:Abstract: Obesity and its co-morbidities are an em
 erging public health concern. The detailed mechani
 stic understanding of energy balance and the devel
 opment of obesity is currently incomplete. The Gen
 etics of Obesity Study (GOOS) recruited thousands 
 of individuals with early-onset extreme childhood 
 obesity. This study led to the identification of r
 are genetic variants affecting key processes in th
 e hypothalamus\, a part of the brain involved in w
 eight regulation and energy balance. To gain furth
 er insights our current work encompasses the genet
 ics of severe obesity and the genetics of thinness
 . We combine large genomic data sets from differen
 t populations and platforms with detailed clinical
  information related to thinness and severe obesit
 y to discover new pathways involved in weight regu
 lation and associated diseases.
LOCATION:MR4\,  Centre for Mathematical Sciences\, Wilberfo
 rce Road\, Cambridge
CONTACT:
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