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CATEGORIES:CMIH Hub seminar series
SUMMARY:Imaging the Molecular Pathology of Alzheimer’s dis
 ease - William Jagust\, UC Berkeley School of Publ
 ic Health
DTSTART;TZID=Europe/London:20180504T140000
DTEND;TZID=Europe/London:20180504T150000
UID:TALK105400AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/105400
DESCRIPTION:Recent advances in molecular imaging using positro
 n emission tomography have permitted the 4-dimensi
 onal mapping of Alzheimer’s disease related pathol
 ogy. The two aggregated proteins\, beta-amyloid an
 d tau\, can now be visualized\, along with the pre
 sumptive consequences of their deposition - brain 
 degeneration and cognitive decline. This talk will
  review both cross sectional and longitudinal data
  concerning how tau and amyloid interact\, and how
  they are related to neurodegeneration and cogniti
 on. The framework for discussion is a sequential m
 odel of biomarker changes. The question of whether
  and how well the observed data fit this model wil
 l be discussed.
LOCATION:MR11\, Centre for Mathematical Sciences
CONTACT:Rachel Furner
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