University of Cambridge > Talks.cam > Centre for Molecular Science Informatics > "CADD & ENAC - A bad hand at Scrabble..?"

  Browse A-Z

Log in

University Account External (via Google)

🔐 Log In

Information on

Subscribing to talksdetails Finding a talkdetails Adding a talkdetails Disseminating talksdetails Help and Documentationdetails

ℹī¸ Information

"CADD & ENAC - A bad hand at Scrabble..?"

Download to your calendar using vCal

If you have a question about this talk, please contact Susan Begg .

Please note that the date of this seminar has been changed

Cystic Fibrosis is a disease caused by genetic defects in the CFTR protein. The manifestation of those defects in the lung is a reduction in airway hydration producing a viscous mucal layer and ineffective mucocilliary clearance leading to pathogenic build up in the lungs. The Epithelial Sodium channel (ENaC) is instrumental in the osmotic gradients required for normal airway hydration and can serve as an alternative target for the mitigation of CF. The various approaches taken to develop inhibitors of ENaC will be described as well as the recent developments in the structural elucidation of the related family member ASIC .

This talk is part of the Centre for Molecular Science Informatics series.

This talk is included in these lists:

Note that ex-directory lists are not shown.

Other lists

Engineering Department - Lecture Room - LR0, Baker Building Seminar room 1, Hopkins Building, Departmentt of Biochemistry, Downing Site, University of Cambridge CB2 1QW Main Lecture Theatre, Old Divinity School, St John's College, Cambridge CB2 1TP, UK

Other talks

Title to be confirmed Coming soon The Play Paradox: How video games build better humans Group Work A Data-Centric Approach to AI Adaptation and Alignment How Far Can Good Go Without God? The Limits of a Naturalistic Ethic
 

Š 2006-2025 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity