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Leverhulme Lecture: The translocation of polymers across nanometer sized pores in membranes

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If you have a question about this talk, please contact Shery Huang.

The operation of sub-cellular processes in living organisms often require the transfer of bio-polymers across impermeable lipid membranes. The emergence of new experimental techniques for manipulation of single molecules at nanometer scales have made possible in vitro experiments that can directly probe such translocation processes in cells as well as in synthetic systems. Some of these ideas have spawned novel bio-technologies with many more (such as ultra fast DNA sequencing) likely to emerge in the near future. In this talk I would review some of these experiments and attempt to provide a quantitative understanding of the data in terms of physical laws, primarily mechanics and electrostatics.

This talk is part of the BSS Formal Seminars series.

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