Immune alterations in first-episode psychosis and the effects of natalizumab: A neuroimaging study with concurrent CSF measures

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• Dr Yuya Mizuno, King's College London
• Thursday 20 November 2025, 12:30-13:30
• Hybrid (in-person at the Herchel Smith Building and online via zoom).

If you have a question about this talk, please contact Oliver Knight.

It is hypothesised that microglia, the primary immune cells in the brain, play a key role in the pathophysiology of schizophrenia. To address this, we investigated the effects of 3-month treatment with the monoclonal antibody natalizumab on a PET biomarker of microglia, CSF cytokines, and symptom measures in people with first-episode psychosis. I will be presenting unpublished findings from this study and future directions.

This talk is part of the Department of Psychiatry & CPFT Thursday Lunchtime Seminar Series series.

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