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Modelling collective cell movement in early development

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  • UserPhilip Maini, University of Oxford
  • ClockMonday 03 November 2025, 14:30-15:30
  • HouseOnline.

If you have a question about this talk, please contact Jia CHEN .

Abstract: Collective cell movement is a common phenomenon in biology, occurring n embryonic development, wound healing and disease. In a collaboration with experimentalists for over a decade we have been carrying out an interdisciplinary study of the chick cranial neural crest. I will show how a simple agent-based mathematical model, combined with experimental studies, has led to new insights into how these neural crest cells move in a coherent stream. In particular we identified phenotypic heterogeneity and switching as being key features of the process, as well as investigating mechanisms that confine the cells to the corridor along which they move.

This talk is part of the Morphogenesis Seminar Series series.

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Ray Dolby Centre, 3rd floor seminar room, PHY-RDC C3.002 C302, Sulston Building, Wellcome Genome Campus, Hinxton. CB10 1SA Roger Needham Room , Wolfson College

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