Abstract

Friday 24 October, 13:00 – 14:00

Speaker: David Hodson, University of Oxford

Talk Title: Interrogating GPC Rs from the Single Molecule to the Whole Animal

Biography: David Hodson is the Robert Turner Professor of Diabetic Medicine at the Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford. Originally a Veterinary Surgeon by training, David undertook postdoctoral studies at the CNRS , Montpellier, before establishing his independent laboratory at Imperial College London as a Diabetes UK RD Lawrence Fellow. The lab is focused on developing and using novel technologies to address challenging problems in cellular metabolism, with translational relevance for patients. We have particular interest in glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) receptors, two related class B G protein-coupled receptors. Both receptors are involved in the regulation of glucose homeostasis, food intake and inflammation and as such have become major drug targets for the treatment of diabetes and obesity. We are currently seeking to understand where and how GLP -1 and GIP receptors operate within complex tissues such as the pancreas and brain.