Remodeling of Mitochondria during Microbial Infection

Add to your list(s) Download to your calendar using vCal

• Dr Lena Pernas | MPI, Cologne
• Wednesday 05 April 2023, 15:00-16:00
• MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY.

If you have a question about this talk, please contact Hannah Burns.

The rewiring of mitochondrial metabolism serves as an innate immune-type defense mechanism that restricts the growth of the human parasite Toxoplasma gondii. We recently reported a previously undescribed structure we term SPOT (structure positive for outer mitochondrial membrane (OMM) that emerges from the OMM during infection. We propose that Toxoplasma hijacks the formation of SPO Ts, a cellular response to OMM import stress, to counteract mitochondrial nutrient defense and promote its growth. Here, I discuss the fate and function of these peculiar structures.

This talk is part of the MRC Mitochondrial Biology Unit Seminars series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• CamBridgeSens
• Cambridge talks
• Life Science Interface Seminars
• MRC MBU, Level 7 Lecture Theatre, The Keith Peters Building, CB2 0XY
• MRC Mitochondrial Biology Unit Seminars
• Trust & Technology Initiative - interesting events

Note that ex-directory lists are not shown.