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Dr Ritwick Sawarkar; Group Leader, MRC Toxicology Unit, University of Cambridge
Wednesday 31 March 2021, 15:00-16:00
The chromatin response of human cells to SARS-CoV-2 et al
â ī¸ Important: This webinar will be online via zoom. No registration required.
- đ¤ Speaker: Dr Ritwick Sawarkar; Group Leader, MRC Toxicology Unit, University of Cambridge
- đ Date & Time: Wednesday 31 March 2021, 15:00 - 16:00
- đ Venue: Zoom Seminar
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Bobbie Claxton
Abstract
A variety of environmental stressors and infections cause global transcriptional downregulation in human cells, a phenomenon we termed as Stress-Induced Transcriptional Attenuation (SITA). In the talk, I will discuss our work on understanding the mechanism underlying SITA that has led us to uncover novel nuclear condensates formed by liquid-liquid phase separation. Similar transcriptional downregulation is also seen in lung cells upon SARS -CoV-2 infection, identifying therapeutic avenues.
Please click here to join the webinar live: https://zoom.us/j/94864392896
Series This talk is part of the Babraham Seminar series.
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