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Human Immunity – one cell at a time

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  • UserDr Sarah Teichmann, Wellcome Sanger Institute, Hinxton
  • ClockThursday 29 April 2021, 13:30-14:30
  • HouseZoom meeting.

If you have a question about this talk, please contact Caroline Newnham.

Host: Anne Ferguson-Smith

Dissecting immune responses by next generation sequencing methods at single cell resolution provides novel insights into cell states, including antigen receptor diversity, cell-cell interactions in tissues, and how cellular phenotypes change in the context of adaptation from lymphoid to non-lymphoid tissues. We elucidate in detail development of immunity and how the immune system contributes to tissue homeostasis, as well as gaining a deepr understanding of immunity to infection in the mucosa and blood. The immune compartment is fast-evolving across species and highly variable in humans, and single cell genomics allows us to understand the phenotypic impact of this variability at single cell resolution.

This talk is part of the Genetics Seminar series.

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