Morphogenesis Seminar Series 2021-01-18 14:30: First a war then a dance: How sensory organs take shape (Anna Erzberger (EMBL Heidelberg, Germany)) 2021-01-25 14:30: Cell shape, cell division and the development of early embyos (Nicolas Minc) 2021-02-01 14:30: From cell dynamics to robust tissue folding (Magali Suzanne) 2021-02-08 14:30: Generating order out of (pseudo)chaos during vertebrate retinal lamination (Caren Norden) 2021-02-15 14:30: The importance of being edgy: directional growth control in Arabidopsis lateral roots (Charlotte Kirchhelle) 2021-02-22 14:30: Two signals converge on a nerve cell’s path: The interplay between chemical and mechanical signals in the developing brain (Eva Pillai) 2021-03-01 14:30: Against the grain; Modeling seed growth control as an mechano-sensitive incoherent feedforward loop. (Olivier Ali) 2021-03-08 14:30: The evolution of cell division: from archaea to eukaryotes (Buzz Baum) 2021-04-26 14:30: ‘Fine-tuning cell mechanics at the onset of collective cell motion’ (Elias H Barriga, Group Leader at Mechanisms of Morphogenesis Lab, Instituto Gulbenkian de Ciência (IGC), Oeiras, Portugal) 2021-05-04 14:30: Stochastic gene expression drives mesophyll protoplast regeneration (Yuling Jiao, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences) 2021-05-10 14:30: Wisdom of the crowd – Mechanisms that coordinate individual cell movements for epithelial migration (Sally Horne-Badovinac, University of Chicago) 2021-05-17 14:30: Size sensing in biological systems- new insights from planarians (Jochen Rink, Max Planck Institute for Biophysical Chemistry, Gottingen,Germany.) 2021-05-24 14:30: Morphogenesis of the mouse and human embryo beyond implantation (Matteo Molè) 2021-06-01 14:30: Stretching out the embryo - Anterior expansion and posterior addition to the notochord mechanically coordinate embryo axis elongation (Susie McLaren, University of Cambridge) 2021-06-01 14:30: Regulation of Phyllotaxis by Auxin Transport Proteins (Henrik Ahl, Sainsbury's laboratory, University of Cambridge) 2021-06-07 14:30: "Investigating the role of Syndecan, a conserved heparan sulphate proteoglycan, in the maintenance and proliferation of progenitor cells in the adult Drosophila midgut" (Buffy Eldridge, PDN, University of Cambridge) 2021-06-07 14:30: "Single-cell morphometrics reveals ancestral principles of notochord development" (Toby Andrews, Department of Zoology, Univeristy of Cambridge) 2021-06-14 14:30: Building organs – emergence of form and fate through local force imbalance (Rashmi Priya, The Francis Crick Institute, London) 2021-10-11 14:30: Cell shape determination: Mechanical competition vs. endogenous genetic programme (Maria Leptin) 2021-10-18 14:30: Morphogenesis and cell ordering in bacterial biofilms (Jing Yan) 2021-10-25 14:30: Matteusz: "Insights into the mechanism and evolution of glial ensheathment" Renske: "Evolution of selfish multicellularity: changes in gene regulation at the origin of multicellularity" (Renske Vroomans; Matteusz Trylinski) 2021-11-08 14:30: Jamie: "A biomechanical switch regulates the transition towards homeostasis in oesophageal epithelium" Ben: "Integrating pattern formation and cell movements in our understanding of morphogenesis" (Ben Steventon, Jamie McGinn) 2021-11-15 14:30: To stay or leave? Cell-to-cell heterogeneity and progenitor’s segregation within the bird embryonic tail (Bertrand Benazeraf) 2021-11-22 14:30: Symplasmic auxin movement and the evolution of plant architecture (Yoan Coudert) 2021-11-29 14:30: POSTPONED*Drivers of Morphological complexity: a Cnidarian Perspective (Aissam Ikmi) 2021-12-06 14:30: Developmental Control of Avian Skin Patterning (Marie Manceau) 2022-01-24 14:30: Characterization of a Mechanical Hotspot for Cell Plate Guidance Near an Adjacent Three-Way Junction (Marie-Cécile Caillaud, CR CNRS) 2022-01-31 14:30: Emergence of a left-right symmetric body plan during embryonic development (Sundar Naganathan (EPFL, Lausanne, Switzerland) ) 2022-01-31 14:30: CADHERIN mediated AMIS localisation - Using mouse embryonic stem cells 3D culture as a model (Xuan Liang (PDN, Cambridge University) ) 2022-02-07 14:30: Adhesion-regulated junction slippage controls cell intercalation dynamics in an Apposed-Cortex Adhesion Model (Alexander Nestor-Bergmann (PDN, University of Cambridge)) 2022-02-07 14:30: Breaking the barrier: CSF-producing choroid plexus organoids model pathogen and drug entry to the brain (Laura Pellegrini (LMB, Cambridge)) 2022-02-14 14:30: Understanding the role of the extracellular matrix: from elasticity to viscoelasticity (Alberto Elosegui-Artola (Francis Crick Institute & King’s College London, London, UK) ) 2022-02-21 14:30: Mechanisms generating robustness in plant organ size and shape (Adrienne Roeder ) 2022-02-28 14:30: The fossil origins of eukaryotic morphogenesis: exploring the beginnings of complex multicellularity in the Holozoa (Paul K. Strother (Boston College) ) 2022-03-07 14:30: Getting into shape: new insights into morphological patterning from the Drosophila wing (Natalie Dye (POL Dresden) ) 2022-04-25 14:30: Composite morphogenesis: how can a tissue fold and extend at the same time (Matteo Rauzi (IBV, Nice)) 2022-05-09 14:30: Cell-type-specific behaviour underlies cellular growth variability in plants (Daniel Kierzkowski Montreal University ) 2022-05-16 14:30: Multicellular coordination in context (Takashi Hiiragi, Hubrecht Institute, Utrecht, Netherlands ) 2022-05-23 14:30: Drivers of cnidarian morphogenesis ( Aissam Ikmi (EMBL, Heidelberg)) 2022-05-30 14:30: Organoids – how can they shed light on immune-mediated development and disease? (Geraldine Jowett (Gurdon Institute, Cambridge) ) 2022-05-30 14:30: Differentiation of the extra-embryonic endoderm is required for development of the pluripotent epiblast (Antonia Weberling (PDN, Cambridge) ) 2022-06-06 14:30: CANCELLED!!!!!! Cell invasion: a casualty of dysregulated cell extrusion (Jody Rosenblatt, Randall’s Division for Cell and Molecular Biophysics, King’s College London.) 2022-06-13 14:30: 4D reconstruction of developmental trajectories (Giovanni Dalmasso (EMBL Barcelona, Sharpe Lab) ) 2022-06-13 14:30: Exploring variation in neural crest development among East African cichlid fishes (Aleksandra Marconi (Zoology Department, Santos lab) ) 2022-10-17 14:30: Multi-organ FGF crosstalk orchestrates the construction of the water conserving cryptonephridial complex in a beetle (Robin Beaven, University of Edinburgh) 2022-10-17 14:30: How tissues orchestrate growth and morphogenesis – lessons from the vertebrate retina  ( Mauricio Rocha Martins (Instituto Gulbenkian Ciência (IGC), Oeiras, Portugal) ) 2022-10-24 14:30: Cell extrusion—an exciting start to the end of life (Jody Rosenblatt, King's College London) 2022-10-31 14:30: Submerged by 4-way junctions: how the early embryo of the brown alga Saccharina e-copes (Bénédicte Charrier ) 2022-11-07 14:30: Computational Models of the Development of the Central Nervous System (Dagmar Iber, ETH Zurich (Computational Biology) ) 2022-11-14 14:30: Single-cell phenomics reveals behavioural and mechanical heterogeneities underpinning migratory activity during mouse anterior patterning (Shankar Srinivas, Department of Physiology, Anatomy and Genetics, University of Oxford ) 2022-11-21 14:30: Understanding how flowering plants build communication devices on their petals (Lucie Riglet, Sainsbury's Laboratory, Cambridge University) 2022-11-21 14:30: Branching morphogenesis of the lung: tales of the sculptor and the sculpture (Katharine Goodwin (Princeton, MRC LMB) ) 2022-11-28 14:30: Dynamics and mechanics of cell shape changes during cellular state changes (Ewa Paluch, Department of Physiology, Development and Neuroscience, University of Cambridge. ) 2023-01-23 14:30: Evolution of Morphogenesis: the case of cephalic furrow (Pavel Tomancak (MPI CBG, Dresden, Germany & CEITEC, Brno, Czech Republic)) 2023-01-25 14:30: Title to be confirmed (Kyogo Kawaguchi ) 2023-01-30 14:30: Mechano-chemical feedbacks in plant regeneration (Kalika Prasad (Indian Institute of Science Education and Research, Pune, India)) 2023-02-13 14:30: Cephalo-pelvic integration in hybrid mouse models and implications for human obstructed labour (Eva Zaffarini (McCaig Institute, University of Calgary)) 2023-02-13 14:30: Junctional Remodelling in Vascular Morphogenesis (Maria Paraskevi Kotini (Biozentrum, Basel Switzerland)) 2023-02-20 14:30: Building and Breaking the Neural Tube (Clare Buckley (PDN, University of Cambridge) ) 2023-02-27 14:30: On the specification of leaf dorsiventrality (Agata Burian (University of Silesia in Katowice) ) 2023-03-06 14:30: Life and death of cells a mystery solved through biomechanics (Lakshmi Balasubramaniam (Gurdon Institute, University of Cambridge) ) 2023-03-06 14:30: Mechanics and patterning combine to orient cell divisions in a planar polarised epithelium (Guy Blanchard, PDN, University of Cambridge) 2023-03-13 14:30: Connecting spaces and scales in embryos (Jesse Veenvliet ) 2023-04-24 14:30: Patterning and folding of intestinal villi by active mesenchymal dewetting (Tyler Huycke (UCSF)) 2023-04-24 14:30: Modelling active morphogenesis of patterned epithelia ( Diana Khoromskaia (Crick Institute, London)) 2023-05-15 14:30: You shall not pass! How ectoderm patterning modulates lateral mesendoderm migration in the early zebrafish gastrula. (Stefania Tavano, ISTA Vienna, Austria ) 2023-05-15 14:30: STOMATA DIVISION ORIENTATION: INTERPLAY BETWEEN GEOMETRY, GROWTH, AND MECHANICAL STRESS (Leo Serra The Sainsbury Laboratory, University of Cambridge, Cambridge CB2 1LR, United Kingdom ) 2023-05-22 14:30: Are plant cells balloons? A biomechanical perspective on plant cell growth. (Yuchen Long ) 2023-06-05 14:30: Opening doors and boosting energy: cellular programs that enable macrophage tissue infiltration. (Daria Siekhaus, ISTA, Vienna Austria) 2023-06-12 14:30: Cued or cueless? Mechanisms that shape mesoderm and enable cell ingression (Sevan Hopyan ) 2023-06-19 14:30: Connecting spaces and scales in embryos (Jesse Veenvliet) 2023-10-09 14:30: Role of mechano-gated ion channels in epithelial tissue morphogenesis (Prof. Jorg Grosshans, Philipps University Marburg, Germany) 2023-10-16 14:30: Dr. Natasha Shylo-Morphological changes and two Nodal paralogs drive left-right asymmetry in the squamate veiled chameleon; Dr. Nicole Edwards-Discovering the developmental basis of trachea-esophageal birth defects: evidence for endosomeopathies. (Dr. Natasha Shylo, Stowers Institute for Medical Research & Dr. Nicole Edwards, Cincinnati Children's Hospital Medical Center) 2023-10-23 14:30: Mitotic rewiring on evolutionary timescales (Dr. Gautam Dey, EMBL) 2023-10-30 14:30: Coordinated alternative splicing in development, featuring Transformer2b and ciliary tissues.-Dr. Charlotte Softley. (Dr. Holliday Lovegrove, Univ of Manchester & Dr. Charlotte Softley, University Clinic Freiburg) 2023-11-07 14:30: Drosophila axis extension is robust to an orthogonal pull by invaginating mesoderm-Dr. Claire Lye; Decoding cell fates in the shoot apical meristem through single-nuclei transcriptomics-Dr. Sebastian Moreno. (Dr. Sebastian Moreno, Sainsbury Laboratory and Dr. Claire Lye, PDN) 2023-11-13 14:30: Turning biological morphology into numbers (Dr. Virginie Uhlmann, EMBL) 2023-11-20 14:30: How Cell and Tissue Geometry Influences Morphogenesis (Dr. Yohanns Bellaiche, Institut Curie ) 2023-11-27 14:30: Multicellular and extracellular matrix dynamics underlying skin morphogenesis. (Dr. Hironobu Fujiwara, RIKEN Center for Biosystems Dynamics Research (BDR), Kobe, Japan) 2024-01-22 14:30: From microscopy images to mechanical models of tissues and back (Hervé Turlier, Center for Interdisciplinary Research in Biology, College de France) 2024-01-29 14:30: *CANCELLED*: Cortical microtubules shape cell walls to support a wide range of functions (EE (Eva) Deinum, Department of Plant Sciences, Wageningen University & Research) 2024-02-05 14:30: Echinoderm embryos to model epithelial morphogenesis: from cell biology to evo-devo (Vanessa Barone, Hopkins Marine Station, Biology Department, Stanford University) 2024-02-12 14:30: Temporal patterning during development and tumorigenesis (Cedric Maurange, IBDM, Marseille,France) 2024-02-19 14:30: Insights into the mechanism of hind limb initiation in Xenopus laevis (John Young, Department of Biology, Simmons University) 2024-02-26 14:30: CRISPy Chickens-screening fate transitions from caudal epiblast to neural tube-Ashley Libby; Coupling mitochondrial energy metabolism to branching morphogenesis in the developing avian lung-Bezia Lemma. (Ashley Libby, Briscoe lab,The Francis Crick Institute; and Bezia Lemma, Nelson lab, Princeton University) 2024-03-04 14:30: Holly Lovegrove: Mitosis in Motion: Cell division during collective cell migration; Leo Otsuki: Puzzling out tissue regeneration. (Holly Lovegrove, University of Manchester and Leo Otsuki, Elly Tanaka lab, IMP, Vienna ) 2024-03-11 14:30: Mechanisms underlying colour pattern variation within and between species of cichlid fishes (Emilia Santos, Department of Zoology) 2024-04-29 14:30: Playing with Patterns via VisualPDE (Andrew Krause, Durham University) 2024-05-13 14:30: Mechanisms and mechanics of morphogenesis (Katja Röper, University of Cambridge) 2024-05-20 14:30: You are not encoded - a biological theory of form (Alan Rodrigues, Rockefeller University) 2024-05-28 14:30: Multiscale mechanical linkage elongates tissues in development (Shinuo Weng, Johns Hopkins University) 2024-06-03 14:30: Wolfram Pönisch-Deciphering the role of noise in cell shape changes during epithelial-to-mesenchymal transition; Constance Le Gloanec-Protect and provide: the dual role of the cauline leaf. (Constance Le Gloanec and Wolfram Pönisch) 2024-06-10 14:30: Cortical microtubules shape cell walls to support a wide range of functions (Eva Deinum) 2024-10-15 14:30: Non-apical mitoses contribute to cell delamination during mouse gastrulation (Isabelle Migeotte IRIBHM - Jacques E. Dumont Institut Interdisciplinaire en biologie humaine et moléculaire - Université Libre de Bruxelles, Brussels, BE ) 2024-10-21 14:30: Developmental Constraint Underlying the Evolution of Morphological Diversity (Madelaine Bartlett, Sainsbury Laboratory, University of Cambridge ) 2024-10-28 14:30: Duy-Chi Trinh-How do flowers close themselves: the story from Arabidopsis; Liyuan Sui-Cell tilting: A novel mechanism driving three-dimensional epithelial morphogenesis (Duy-Chi Trinh-ENS de Lyon, France; University of Science and Technology of Hanoi, Vietnam & Liyuan Sui-Postdoc from Christian Dahmann’s Lab School of Science, Technische Universität Dresden) 2024-11-04 14:30: Noah Mitchell - Mapping the Mechanics and Dynamics of Gut Morphogenesis; Stefan Harmansa - Shaping Growing Tissues by Basement Membrane Mechanics (Noah Mitchell - University of Chicago & Stefan Harmansa-Living Systems Institute - University of Exeter United Kingdom) 2024-11-11 14:30: Bioengineering neural organoid morphogenesis (Adrian Ranga) 2024-11-18 14:30: Chemo-mechanical signal in embryo development (Roberto Mayor) 2024-11-25 14:30: Modelling Self-Organisation (Jeremy Green-King’s College London, London, United Kingdom) 2025-01-27 14:30: Morphogenetic control of cellular differentiation during gastrulation (Marta Shahbazi, MRC Laboratory of Molecular Biology, Cambridge, UK) 2025-02-03 14:30: Fundamental principles during the egg-to-embryo transition (Andrea Pauli, IMP (Institute of Molecular Pathology), Vienna, Austria) 2025-02-10 14:30: Akantsha Jain-Unveiling the choreography of human brain development;Yamini Ravichandran-Topology changes of the regenerating Hydra define actin nematic defects as mechanical organizers of morphogenesis (Akantsha Jain,Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland; Yamini Ravichandran,University of Geneva, Switzerland) 2025-02-17 14:30: Juan Alonso-Serra -Hydraulic patterns in plant development; Ana Patricia Ramos-Forming an Eye: from cell behaviour to tissue shape changes. (Juan Alonso-Serra,University of Helsinki; Ana Patricia Ramos, Instituto Gulbenkian de Ciência (IGC), Oeiras, Portugal ) 2025-02-24 14:30: Developmental patterning of head-like inflorescences in Asteraceae (Paula Elomaa,University of Helsinki ) 2025-03-03 14:30: Deciphering how complex organ form emerges in development (Timothy Saunders) 2025-03-10 14:30: Title to be confirmed (Fengzhu Xiong) 2025-03-19 16:00: From active surfaces to evo-devo-mechanobiology (Guillaume Salbreux, University of Geneva, Switzerland ) 2025-05-12 14:30: Collective cell behaviors in mammalian intestinal morphogenesis (Kaelyn Sumigray, Department of Genetics at Yale School of Medicine) 2025-05-19 14:30: For both titles please look in the abstract session below. (Katie Goodwin-MRC LMB; Miguel Ángel Ortiz Salazar-MRC LMB) 2025-05-27 14:30: Scaling life: How Single Cells Orchestrate Tissue-Level Coordination (Prisca Liberali, FMI) 2025-06-02 14:30: Maik Bischoff-Plexin/Semaphorin Antagonism Orchestrates Collective Cell Migration and Organ Sculpting by Regulating Epithelial-Mesenchymal Balance; Harry McNamara-Decoding and controlling self-organization in stem cell models of embryonic development (Maik Christian Bischoff, UNC, Mark Peifer lab; Harry McNamara, Yale University) 2025-06-09 14:30: Ana Patricia Ramos-Forming an Eye: from cell behaviour to tissue shape changes; Kumud Saini-Temperature Regulation of Cell Cycle and Growth Dynamics in Arabidopsis (Kumud Saini, Robinson Lab, Sainsbury Laboratory & Ana Patricia Ramos, IGC, Portugal ) 2025-06-16 14:30: Mechano-hydraulic control of mammalian folliculogenesis (Chai Jou (Joe) Chen (MBI Singapore) (co-hosted with TLM) ) 2025-10-13 14:30: Title to be confirmed (Anne Grapin-Botton, Max Planck Institute of Molecular Cell Biology and Genetics) 2025-10-20 14:30: Building and extending the body axis: the role of tissue Interfaces (Pierre-François Lenne, IBDM and Turing Center for Living Systems, Aix Marseille Univ. & CNRS, Marseille, France ) 2025-10-27 14:30: Min Ya-The Moment Symmetry Breaks: Spatiotemporal Dynamics of CYCLOIDEA Expression During Early Floral Development; Baptiste Tesson-Complementary Mechanical Identities from Iterative BMP Signaling Ensure Robust Morphogenesis. (Min Ya; Baptiste Tesson) 2025-11-03 14:30: Modelling collective cell movement in early development (Philip Maini, University of Oxford) 2025-11-10 14:30: Mechanics of blastocyst morphogenesis (Jean-Léon Maître, Institut Curie) 2025-11-17 14:30: Luca Guglielmi-Modelling Neuronal Morphogenesis Across Species: a Purkinje Cell’s Journey to Utmost Complexity; Susannah McLaren-Spatially organised cell behaviours in morphogenesis and symbiosis (Luca Guglielmi; Susie McLaren ) 2025-11-24 14:30: Meng Zhu-Maternal oxygen levels regulate the timing of limb development in amniote species; Alex Plum-Morphogen patterning in dynamic tissues (Meng Zhu; Alex Plum) 2025-12-01 14:30: Patterns and form:Lessons from plants. (Neha Bathia) 2026-01-26 14:30: Margot Smit: Arrested Development: temporal regulation of cell identity during plant embryogenesis; Susan Wopat: The zebrafish gastrula is shaped by stationary and germ layer–specific tissue flows (Margot Smit, Susan Wopat) 2026-02-02 14:30: Molecular and cellular scale symmetry breaking in planar polarity (or why the hairs all point the same way on the wing of a fly) (David Strutt, School of Biosciences, University of Sheffield, UK) 2026-02-09 14:30: Postponed: How Mechanics Made Archaea Multicellular (Postponed: Alex Bisson, Department of Biology, Indiana University ) 2026-02-16 14:30: Spontaneous shape transformations of active surfaces (Alexander Mietke, University of Oxford) 2026-02-23 14:30: Marc Trani Bustos: Building the mammalian embryo body: tissue surface mechanics constrains proliferation-driven forces to guide axial elongation; Denis Krndija-“Cracking” the Gut Epithelium: How Goblet Cells Mechanically Disrupt the Gut Barrier. (Marc Trani Bustos, Denis Krndija) 2026-03-02 14:30: Feline Lindhount: Linking human neurodevelopmental timing and evolution, James Fitzsimmons: Brassinosteroid controls leaf air space patterning non-cell autonomously by promoting epidermal growth (Feline Lindhount, James Fitzsimmons) 2026-03-09 14:30: Deciphering the principles of epithelial tissue organization (Delphine Delacour)