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CATEGORIES:Adrian Seminars in Neuroscience
SUMMARY:TODAY Adrian Seminar: &quot\;Synaptic plasticity a
 nd memory&quot\; - Tim Bliss\, University College 
 London
DTSTART;TZID=Europe/London:20180205T163000
DTEND;TZID=Europe/London:20180205T180000
UID:TALK99196AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/99196
DESCRIPTION:There is now overwhelming evidence that memories a
 re stored in the mammalian brain by the agency of 
 synaptic plasticity – the process by which activit
 y in cortical circuits leads to long-term changes 
 in synaptic efficacy.  I will trace the origins of
  these ideas from the work of Ramon y Cajal in the
  late 19th century\, through Hebb’s trenchant enca
 psulation of the widely held hypothesis that synap
 tic activity itself must engender changes is synap
 tic function\, to the first identification of ‘Heb
 bian’ synapses in the hippocampus in the 1970s.  S
 ince then an enormous amount has been learned abou
 t the cellular mechanisms underlying long-term pot
 entiation (LTP) and long-term depression (LTD) at 
 hippocampal synapses.  In my talk I will briefly s
 ummarize these advances and go on to discuss recen
 t work which has sought to establish how the physi
 ological phenomena of LTP and LTD relate to memory
  and learning in the behaving animal.\n\n
LOCATION:The Hodgkin Huxley Seminar Room\, Department of Ph
 ysiology Development and Neuroscience
CONTACT:Lyn Dakin
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