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CATEGORIES:BSS Formal Seminars
SUMMARY:Polymer Physics and DNA Topology - Professor Giova
 nni Dietler\, Laboratoire de Physique de la Matièr
 e Vivante\, Institut de Physique de la Matiere Com
 plexe\n\, Ecole Polytechnique Fédérale de Lausanne
 \, Switzerland
DTSTART;TZID=Europe/London:20070427T141500
DTEND;TZID=Europe/London:20070427T151500
UID:TALK6852AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/6852
DESCRIPTION:DNA appears in linear\, circular and knotted forms
 \, depending on the situation and conditions. It i
 s therefore an excellent playground for polymer ph
 ysics to test theoretical concepts. In the present
  lecture\, I will first focus on the properties of
  linear DNA and show that critical exponents descr
 ibing the divergence of the end-to-end distance ca
 n be determined from Atomic Force Microscopy image
 s of DNA and that the end-to-end distance distribu
 tion as a function of the DNA length can also be d
 etermined. Then\, the properties of knotted DNA in
  respect to the critical exponents and the localiz
 ation of the knot crossings will be reported: I wi
 ll show that probably two universality classes exi
 st in this case and that localization of the knot 
 crossings could explain the activity of the topois
 omerases. At the end of the lecture\, gel electrop
 horesis of DNA knots will be discussed and simulat
 ion as well as experiments will be presented where
  the knot complexity and its toopology play an ess
 ential role.
LOCATION:IRC in Superconductivity Seminar Room\, Cavendish 
 Laboratory
CONTACT:Jurij Kotar
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