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CATEGORIES:Wolfson College Science Society
SUMMARY:How does cancer become an infectious disease? - Dr
  Hannah Siddle (Dpt of Pathology\, Cambridge Unive
 rsity)
DTSTART;TZID=Europe/London:20131206T181500
DTEND;TZID=Europe/London:20131206T191500
UID:TALK48033AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/48033
DESCRIPTION:An aggressive contagious cancer has emerged in the
  Tasmanian devil\, a carnivorous marsupial endemic
  to the island of Tasmania.  Known as Devil Facial
  Tumour Disease or DFTD\, the disease is character
 ised by the rapid growth of large and disfiguring 
 tumours around the face and neck of host devils\, 
 causing close to 100% mortality and rapid decline 
 of the Tasmanian devil population. Naturally occur
 ring contagious cancers\, where tumour cells pass 
 between individuals\, are rare as the vertebrate i
 mmune system is very good at detecting and destroy
 ing foreign cells\, just as it detects pathogens. 
 We have been investigating how DFTD cells so succe
 ssfully evade the host devil immune system\, allow
 ing the tumour cells to pass between devils and qu
 ickly establish new tumours. Based on these studie
 s we are developing a vaccine that could rescue th
 e Tasmanian devil in the wild and our findings may
  also have implications for understanding other ad
 vanced\, drug and immunotherapy resistant tumours.
LOCATION:Seminar Room\, Wolfson College
CONTACT:Dr Maria M Caffarel
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