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CATEGORIES:Plant Sciences Departmental Seminars
SUMMARY:Plant Metabolomics- an update - Alisdair Fernie\, 
 Max-Planck-Institute\, Golm
DTSTART;TZID=Europe/London:20130207T130000
DTEND;TZID=Europe/London:20130207T140000
UID:TALK39041AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/39041
DESCRIPTION:Metabolomics approaches enable the parallel assess
 ment of the levels of a broad range of metabolites
  and have been documented to have great value in b
 oth phenotyping and diagnostic analyses in plants.
  These tools have recently been turned to evaluati
 on of the natural variance apparent in metabolite 
 composition. Here\, I will describe progress made 
 in the identification of the genetic determinants 
 of plant chemical composition\, focussing on the a
 pplication of metabolomics strategies and their in
 tegration with other high-throughput technologies.
  I will use two examples to illustrate this. First
 ly\, by use of the quanitative trait loci approach
  I will describe work we and others have done to d
 elineate the genetic underyling metabolite composi
 tions (and its relationship with yield) in tomato.
  In the second part of my lecture I will describe 
 more recent work in which we utilized natural vari
 ance\, recombinant inbred lines and knockout mutan
 ts in combination with a broad range of metabolomi
 cs techniques to define novel phenylpropanoid path
 way in the model plant Arabidopsis. Perhaps more i
 mportantly we were able to functionally demonstrat
 e that the products of these pathways conferred UV
 -B resistance a fact that gave strong hints as to 
 the processes of natural selection working at the 
 metabolite level. These two examples\, hopefully\,
  illustrate that metabolomics represents an import
 ant addition to the tools currently employed in ge
 nomics-assisted selection for crop improvement. 
LOCATION:Department of Plant Sciences\, Large Lecture Theat
 re
CONTACT:Jill Harrison
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