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CATEGORIES:MRC LMB Neurobiology Seminars
SUMMARY:Multiscale Imaging of the Nervous System: Where is
  the Dark Matter - Mark Ellisman\, Professor of Ne
 urosciences\, Director\, National Center for Micro
 scopy and Imaging Research and Center for Research
  in Biological Systems\, University of California 
 at San Diego
DTSTART;TZID=Europe/London:20120921T110000
DTEND;TZID=Europe/London:20120921T120000
UID:TALK38949AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/38949
DESCRIPTION:A grand goal in neuroscience research is to unders
 tand how the interplay of structural\, chemical an
 d electrical signals in and between cells of nervo
 us tissue gives rise to behavior. We are rapidly a
 pproaching this horizon as neuroscientists make us
 e of an increasingly powerful arsenal of tools and
  technologies for obtaining data\, from the level 
 of molecules to nervous systems\, and engage in th
 e arduous and challenging process of adapting and 
 assembling neuroscience data at all scales of reso
 lution and across disciplines into computerized da
 tabases. This talk will highlight projects where d
 evelopment and application of new contrasting meth
 ods and imaging tools have allowed us to see other
 wise hidden relationships between cellular\, subce
 llular and molecular constituents of nervous syste
 ms. New chemistries for carrying out correlated li
 ght and electron microscopy will be described\, as
  well as recent advances in large-scale high-resol
 ution 3D reconstruction with TEM and SEM based met
 hods. The Whole Brain Catalog (WBC)\, a Google Ear
 th-like open-source virtual model of the mouse bra
 in\, will also be described. The WBC is as an exam
 ple of an open access bioinformatics framework and
  web-based tool whose purpose is partly to facilit
 ate integration of 3D image data from multiple mic
 roscopy methods and to enable the linking of infor
 mation derived from other analytical approaches to
  imaging data. 
LOCATION:MRC LMB: Max Perutz Lecture Theatre
CONTACT:
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