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SUMMARY:Toward Better Bone Regeneration: Innovation in Metallic and Cerami
 c Scaffolds - Prof. Donghui Zhu\,
DTSTART:20230929T130000Z
DTEND:20230929T140000Z
UID:TALK205006@talks.cam.ac.uk
CONTACT:Hilde Hambro
DESCRIPTION:Critical-sized bone defects remain a significant challenge in 
 clinical settings for the purpose of regeneration. Although bone grafts ar
 e a viable treatment option\, their clinical application is hindered by su
 rgical risks and the morbidity associated with autologous grafts\, as well
  as limitations in sourcing and the risks of alloimmunity with allogeneic 
 grafts. Various types of scaffolding materials\, including ceramics\, poly
 mers\, metals\, and composite materials\, have been extensively investigat
 ed. While ceramic or polymer scaffolds may be suitable for low-stress load
 ing bone defect sites\, metal scaffolds provide the necessary mechanical s
 upport and stability for high load-bearing scenarios\, such as long bone d
 efects.\nThis seminar will focus on recent advancements in the utilization
  of biodegradable metals and bioactive bone cements as bioresorbable scaff
 olds to enhance bone regeneration. Taking advantages of additive manufactu
 ring techniques\, these scaffolds offer significant potential in the treat
 ment of bone defects\, thanks to their porous\, customizable architecture\
 , and functionalization capabilities. Moreover\, these materials gradually
  corrode while maintaining their mechanical integrity during the critical 
 tissue healing phase\, ultimately dissolving completely once they have ful
 filled their purpose.\n\nBiography:\nDonghui Zhu is a distinguished schola
 r and SUNY Empire Innovation Professor in the Department of Biomedical Eng
 ineering\, Institute for Engineering-Driven Medicine\, Center of Healthy A
 ging\, and Neuroscience Program at SUNY-Stony Brook University. He complet
 ed his Ph.D. in Bioengineering from the University of Missouri-Columbia in
  2006 and then pursued postdoctoral training at the University of Rocheste
 r. Since joining academia in 2010 as a tenure-track faculty member\, Dr. Z
 hu has been committed to the field of biomaterials and tissue engineering.
  Dr. Zhu’s research endeavors span a wide range of medical applications\
 , including medical implants and devices\, regenerative medicine\, and the
 rapies for cardiovascular diseases\, musculoskeletal disorders\, aging\, a
 nd dementia. His groundbreaking research has garnered over $10 million in 
 total extramural research funding and produced more than 100 peer-reviewed
  publications\, establishing him as a leading figure in his field. He is a
 n elected Fellow of the American Heart Association (AHA) and the American 
 Institute for Medical and Biological Engineering (AIMBE). Moreover\, Dr. Z
 hu serves as an editor-in-chief for two prestigious scientific journals\, 
 “Smart Material in Medicine” and “Engineered Regeneration\,” in ad
 dition to his position on the editorial board of numerous scientific journ
 als. He is a member of several federal grant review panels\, including NIH
 \, NSF\, FDA\, and NASA. Through his exceptional research and leadership\,
  Dr. Zhu has made seminal contributions to the field of biomedical enginee
 ring and continues to advance the frontier of regenerative medicine.
LOCATION:Oatley Seminar Room\, Department of Engineering
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