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CATEGORIES:MRC LMB Seminar Series
SUMMARY:LMB Seminar: From regeneration to homeostasis: tis
 sue-scale decision making - Pros. Prisca Liberali
DTSTART;TZID=Europe/London:20240115T110000
DTEND;TZID=Europe/London:20240115T120000
UID:TALK202063AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/202063
DESCRIPTION:Multicellular organisms are composed of cells and 
 tissues with identical genomes but different prope
 rties and functions. They all develop from one cel
 l to form multicellular structures of astounding c
 omplexity. During development\, in a series of spa
 tio-temporal coordinated steps\, cells differentia
 te into different cell types and establish tissue-
 scale architectures and functions. Throughout life
 \, continuous tissue renewal and regeneration is r
 equired for tissue homeostasis\, which also requir
 es fine-tuned spatio-temporal coordination of cell
 s. I will discuss how cellular interactions genera
 te the specific contexts and spatio-temporal coord
 ination underlying development and regeneration an
 d how we specifically investigate what are the mol
 ecular and physical mechanisms that allow a cell\,
  in a tissue\, to sense its complex environment\, 
 to take individual coordinated decisions. Moreover
 \, I will discuss the molecular mechanisms of inte
 stinal organoid self-organization and the role of 
 cell-to-cell variability in populations of differe
 ntiating cells during symmetry breaking.\n\nTwitte
 r/X Handle - @priscaliberali
LOCATION:In person in the Max Perutz Lecture Theatre (CB2 0
 QH) and via Zoom\, link: https://mrc-lmb-cam-ac-uk
 .zoom.us/j/97161414783?pwd=UEhEZUdDSVVLbDU0Q2lPdFh
 PQ3M2UT09
CONTACT:Scientific Meetings Co-ordinator
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