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DTSTART:19700329T010000
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CATEGORIES:Isaac Newton Institute Seminar Series
SUMMARY:Modeling and topological data analysis of pattern 
 formation in fish skin - Alexandria Volkening (Pur
 due University)
DTSTART;TZID=Europe/London:20230809T111500
DTEND;TZID=Europe/London:20230809T121500
UID:TALK201460AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/201460
DESCRIPTION:Pattern formation is present at many scales in bio
 logy\, and here I will focus specifically on eluci
 dating how brightly colored cells interact to form
  skin patterns in zebrafish. Wild-type zebrafish a
 re named for their dark and light stripes\, but mu
 tant zebrafish feature variable skin patterns\, in
 cluding spots and labyrinth curves. All of these p
 atterns form as the fish grow due to the interacti
 ons of tens of thousands of pigment cells\, making
  agent-based modeling a natural approach for descr
 ibing pattern formation. However\, agent-based mod
 els are stochastic and have many parameters\, so c
 omparing simulated patterns and fish images is oft
 en a qualitative process. Here I will show how to 
 apply methods from topological data analysis to ce
 ll-based\, time-dynamic systems. In this talk\, I 
 will overview our models and present quantitative 
 summaries of messy cell-based patterns forming in 
 time.
LOCATION:Seminar Room 1\, Newton Institute
CONTACT:
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