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CATEGORIES:Seminars on Quantitative Biology @ CRUK Cambridge 
 Institute 
SUMMARY:Causality\, Perturbations\, Gene Regulation\, and 
 Drug Repurposing - Caroline Uhler\, Co-Director of
  the Eric and Wendy Schmidt Center at the Broad In
 stitute of MIT and Harvard
DTSTART;TZID=Europe/London:20220328T140000
DTEND;TZID=Europe/London:20220328T150000
UID:TALK166999AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/166999
DESCRIPTION:An exciting opportunity at the intersection of sin
 gle-cell biology and machine learning stems from t
 he growing availability of large-scale perturbatio
 nal data (drugs\, knockouts\, overexpression\, etc
 .). I will present a framework based on causality 
 and autoencoders that can integrate observational 
 and perturbational data and discuss applications t
 o learning gene regulatory networks as well as pre
 dicting the effect of new perturbations. We end by
  discussing how such a framework can be applied fo
 r drug repurposing in the current COVID-19 crisis.
 \n\nhttps://zoom.us/j/94724443844?pwd=c1VyTHlkZWF2
 OCsxUG5oWGlROHJqdz09\n
LOCATION:Zoom
CONTACT:
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