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CATEGORIES:Centre for Physical Biology talks  
SUMMARY:The actin cortex in live cells - Matthieu Piel - M
 atthieu Piel - Institute Curie
DTSTART;TZID=Europe/London:20201119T143000
DTEND;TZID=Europe/London:20201119T153000
UID:TALK154165AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/154165
DESCRIPTION:CPB Seminar\nMatthieu Piel - Institute Curie (Pari
 s)\n\nA thin meshwork of actin filaments form belo
 w the plasma membrane\, forming the cell outer lay
 er also called the cell cortex. This layer produce
 s forces to shape cells and make them motile. Its 
 central function in cell morphogenesis justified i
 ntense studies for now several decades. The quanti
 ty of accumulated knowledge about that structure i
 s thus now huge. Nevertheless\, because it is very
  thin and dense\, detailed observations of the act
 in cortex in live cells have been limited and the 
 assembly of actin structures have mostly been obse
 rved in vitro. Here I will describe what we learne
 d using two novel approaches: 1) observing the act
 in cortex as it forms on the bare membrane of a st
 able bleb induced by cell confinement and 2) pinch
 ing the cortex in live cells between two magnetic 
 beads to measure its thickness and mecanical prope
 rties.\n\n\nRegister here\nhttps://us02web.zoom.us
 /webinar/register/WN_6Af3wv7FQJaoPpwXYs-35g
LOCATION:Zoom
CONTACT:Margarida Rodrigues
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