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SUMMARY:Discovering the gene networks that regulate hunger - Dr Katherine 
 Lawler (IMS\, Cambridge)
DTSTART:20201014T130000Z
DTEND:20201014T140000Z
UID:TALK151039@talks.cam.ac.uk
CONTACT:Samantha Noel
DESCRIPTION:Studying a rare disease with extreme clinical features can lea
 d to new treatments for patients\, and can also uncover underlying mechani
 sms relevant to common disorders and population health. The Genetics of Ob
 esity Study (GOOS\, http://www.goos.org.uk ) recruited thousands of indivi
 duals with severe early-onset childhood obesity and led to the identificat
 ion of rare genetic variants affecting key processes in the hypothalamus\,
  a part of the brain involved in appetite\, weight regulation and energy b
 alance. To gain further insights our current work encompasses the genetics
  of rare severe childhood obesity and the genetics of thinness. We combine
  large genomic data sets from different populations and platforms with det
 ailed clinical information to discover new pathways involved in appetite\,
  weight regulation and associated disorders.
LOCATION:Please get in touch at compbiomphil@maths.cam.ac.uk for joining i
 nformation.
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