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CATEGORIES:MRC Epidemiology and CEDAR Seminars
SUMMARY:The Challenges of Meta-analysing Metabolomics Data
 \; Experiences from the Consortium Of METabolomics
  Studies (COMETS). - Dr Rachel Kelly\, Channing Di
 vision of Network Medicine\, Brigham and Women’s H
 ospital &amp\; Harvard Medical School\, USA.
DTSTART;TZID=Europe/London:20200423T110000
DTEND;TZID=Europe/London:20200423T120000
UID:TALK139972AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/139972
DESCRIPTION:This seminar will be broadcast live online\, pleas
 e register in advance for this meeting:\n\nhttps:/
 /mrc-epid.zoom.us/meeting/register/v5EtceuhqjguMZe
 y9WROpKEW67x29InsYw\n\nAfter registering\, you wil
 l receive a confirmation email containing informat
 ion about joining the meeting (including iCal) fro
 m Zoom.\n\nPlease use your institutional email add
 ress for registration (if possible) and complete y
 our registration at least 30 minutes prior to the 
 seminar so that you will receive the confirmation 
 email/access link before the seminar. Your registr
 ation will be manually checked and approved.\n\nGe
 netics teaches us that for highly-dimensional omic
  technologies sample size is key\, and that necess
 ary sample sizes can best be archived via meta-ana
 lyses. This poses a challenge for metabolomics due
  to its relative nature of measurement\, the lack 
 of a standardized metabolite nomenclature and diff
 erences in metabolome coverage between platforms. 
 The Consortium Of METabolomics Studies (COMETS)\; 
 has developed a novel workflow to deal with these 
 issues for the first time. I will discuss our expe
 riences with COMETS and how we have leveraged thes
 e developments to conduct largest and most compreh
 ensive metabolomics of BMI study to date\, includi
 ng >100\,000 adults from 43 cohorts worldwide.
LOCATION:Online
CONTACT:Paul Browne
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