BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//talks.cam.ac.uk//v3//EN
BEGIN:VTIMEZONE
TZID:Europe/London
BEGIN:DAYLIGHT
TZOFFSETFROM:+0000
TZOFFSETTO:+0100
TZNAME:BST
DTSTART:19700329T010000
RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=-1SU
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0100
TZOFFSETTO:+0000
TZNAME:GMT
DTSTART:19701025T020000
RRULE:FREQ=YEARLY;BYMONTH=10;BYDAY=-1SU
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
CATEGORIES:CMIH Hub seminar series
SUMMARY:Non-contrast Enhanced MRI in Central Nervous Syste
 m - Professor Meiyun Wang
DTSTART;TZID=Europe/London:20190322T140000
DTEND;TZID=Europe/London:20190322T150000
UID:TALK121957AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/121957
DESCRIPTION:In this talk\, the applications of three non-contr
 ast enhanced advanced MR techniques\, including Di
 ffusion Kurtosis Imaging (DKI)\, Strategically Acq
 uired Gradient Echo (STAGE) and a Length and Offse
 t Varied Saturation (LOVARS) in central nervous sy
 stem (CNS) will be summarized. \nDKI has been used
  to measure non-Gaussian diffusion\, which has the
  potential to characterize both normal and patholo
 gic tissue better than diffusion-tensor imaging. S
 ome previous researchers have suggested that DKI m
 ight provide more accurate information about water
  diffusion. Our study showed that mean kurtosis va
 lues may provide additional information and improv
 e the grading of gliomas compared with conventiona
 l diffusion parameters.\nSTAGE is an advanced Susc
 eptibility weighted imaging (SWI) which can provid
 e multi-contrast images in one scan\, such as T1W\
 , PDW\, T1 MAP\, PD MAP\, R2* MAP\, SWI\, and even
  MRA images in 5 minutes. It’s very helpful in ear
 ly detecting and evaluating ischemia\, brain traum
 a and some other CNS diseases.\nLOVARS is a novel 
 Chemical exchange-dependent saturation transfer (C
 EST) technique with variable length of saturation 
 for 1 pair of offsets\, which can detect endogenou
 s macromolecules (e.g. Tumor associated glycoprote
 in MUC-1) and metabolites. Some preliminary studie
 s have showed that LOVARS is not only helpful in e
 arly detection and separation of cerebral ischemia
  and intracranial hemorrhage\, but also in grading
  glioma\, evaluating the therapy effect and even d
 ifferentiating treatment effect from tumor reoccur
 rence. Furthermore\, it can also detect and differ
 entiate cerebral ischemia from intracranial hemorr
 hage at very early stage. So it may have the poten
 tial to improve the diagnostic flow for early stro
 ke. But its post-processing is still complicated.\
 n
LOCATION:MR11\,  Centre for Mathematical Sciences\, Wilberf
 orce Road\, Cambridge
CONTACT:J.W.Stevens
END:VEVENT
END:VCALENDAR