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DTSTART:19700329T010000
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CATEGORIES:Department of Psychiatry &amp\; CPFT Thursday Lunc
 htime Seminar Series
SUMMARY:Primary and Secondary Prevention of Dementia: can 
 we PROTECT our Cognitive Health? - Professor Clive
  Ballard\, Professor of Age-related Diseases\, Col
 lege of Medicine and Health\, University of Exeter
DTSTART;TZID=Europe/London:20190523T123000
DTEND;TZID=Europe/London:20190523T133000
UID:TALK115351AThttp://talks.cam.ac.uk
URL:http://talks.cam.ac.uk/talk/index/115351
DESCRIPTION:As the number of people with dementia continues to
  grow\, and we are still making limited headway in
  the development of disease modifying therapies\, 
 the potential role of prevention is becoming incre
 asingly important.  Our understanding of key facto
 rs associated with increased and reduced risk of d
 ementia has become increasingly clear through rece
 nt meta-analysis and there is some evidence that p
 revention measures are already beginning to mitiga
 te incident rates of dementia within each age grou
 p.  To maximize potential benefits for public heal
 th however\, we need to have mechanisms to evaluat
 e and implement evidence based approaches in a cos
 t-effective way.  To this end we have developed th
 e PROTECT platform – an on-line cohort study in pe
 ople without dementia over the age of 50\, running
  in the UK\, US\, Norway and Hong Kong. We current
 ly have 25\,000 UK participants with serial neurop
 sychology\, mental health assessments\, lifestyle 
 and medical information and DNA -  and the cohort 
 will grow to over 100\,000 people over the next ye
 ar with the international federation. So far\, we 
 have been able to confirm the increased risk of he
 aring loss and depression as risk factors for cogn
 itive decline\, highlight the importance of mild b
 ehavioural impairment as a key risk factor for pro
 gressive decline and begin to identify potential g
 enetic mechanisms and produce evidence demonstrati
 ng the benefit of cognitive training in 2 large RC
 Ts using different training approaches\, with ongo
 ing trials of vitamin D\, physical exercise and nu
 tritional interventions.
LOCATION:Seminar Room\, Herchel Smith Building\, Forvie Sit
 e.
CONTACT:Dr Muzaffer Kaser
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