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University of Cambridge > Talks.cam > Isaac Newton Institute Seminar Series > Modelling Cellular Reaction-Diffusion Kinetics
Modelling Cellular Reaction-Diffusion KineticsAdd to your list(s) Download to your calendar using vCal
If you have a question about this talk, please contact INI IT. This talk has been canceled/deleted Accurate modeling of reaction kinetics is important for understanding the functionality of biological cells. Depending on the particle concentrations and on the relation between particle mobility and reaction rate constants, different mathematical models are appropriate. In the limit of slow diffusion and small concentrations, both discrete particle numbers and spatial inhomogeneity must be taken into account. The most detailed model consists of particle-based reaction-diffusion dynamics, where all individual particles are explicitly resolved in time and space, and particle positions are propagated by diffusion equations, and reaction events may occur only when reactive species are adjacent. For rapid diffusion or large concentrations, the model may be coarse-grained in different ways. Rapid diffusion leads to mixing and implies that spatial resolution is not needed below a certain length scale. This permits the system to be modeled via a spatiotemporal chemical Master equation (STCME), i.e. a coupled set of chemical Master equations acting on spatial sub-volumes. The talk will discuss these different models; in particular, we will see how the STCME description can be derived from particle-based reaction-diffusion dynamics. This talk is part of the Isaac Newton Institute Seminar Series series. This talk is included in these lists:This talk is not included in any other list Note that ex-directory lists are not shown. |
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